The Center for Advanced Microscopy offers comprehensive Laser Capture Microscopy (LCM) services for the biological sciences including a Zeiss Palm MicroBeam IV Laser Capture Microscope and a full range of sample preparation equipment, including a Leica CM 1850 cryostat for fresh tissue sectioning, a Leica RM2125RT microtome for paraffin sectioning and an EMS Precision Pulsed Laboratory Microwave Oven for sample fixation.
The Zeiss Palm MicroBeam IV Laser Capture Microscope provides excellent cell and tissue isolation for downstream analyses, such as RNA, DNA or protein sequencing. The LCM system is configured on a fully automated Zeiss AxioObserver Z1 inverted microscope and is equipped with a 351 nm laser for the tissue microdissection and laser capture. The system is also configured with the RoboMover automated stage, which permits synchronized movement of the sample isolation and collection tube. A full selection of objectives peremits tissue isolation at a range of magnifications in either a brightfield-imaging mode using the AxioCam ICc 1 high-resolution color camera or in a fluorescence-imaging mode using the AxioCam MRm high-resolution low-light camera.
For Laser Capture Microscope services contact Melinda Frame, firstname.lastname@example.org, 517-432-2327.
See our Service and User charges page.